2022 ACC/AHA Guideline for the Diagnosis and Management of ...



cardiac occlusion :: Article Creator

Heart Closure Devices Market Is Anticipated To Be Worth US$ 10.88 Billion By 2033FMI Analyst

The global Heart Closure Devices Market is expected to be valued at US$ 2.71 Billion in 2023. The overall demand for heart closure devices is anticipated to increase at a CAGR of 14.9% between 2023 and 2033, reaching a total of roughly US$ 10.88 Billion by 2033 due to the rise in demand for highly effective procedures among people and the rise in research and development spending for developing innovative and technologically advanced products.

Factors such as an increase in incidence of congenital heart defects, technological advancements in heart closure devices, rise in adoption of MRI procedures, and upsurge in geriatric population are expected to augment the growth of the global heart closure devices market over the analysis period.

On the other hand, high cost of production and stringent regulations associated with these devices limit the market growth. Whereas, an increase in number of heart strokes and development of innovative products by key players are expected to provide lucrative avenues for market expansion in the forthcoming years.

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Furthermore, the utilization of 3D imaging and anatomical models in the manufacturing and planning processes of heart closure devices is gaining prominence in the market. This is expected to change the supply landscape of the industry, attributed to characteristics such as personalization, adaptability, and flexibility provided by using 3D imaging technology.

This in turn decreases the overall prostheses employed per patient along with the procedure time, which makes it a viable option in the production and planning process. Similarly, continuous new product launches as well as approvals along with rapid expansion of healthcare industry across emerging economies will bode well for the market growth in the near future.

Cardiac Occlusion Devices are medical devices used to close a hole or defect in the wall between the two upper chambers of the heart, known as the atria. These devices are used to treat a condition called atrial septal defect (ASD) or patent foramen ovale (PFO).

Key Takeaways from the Market Study

  • Global heart closure devices market was valued at US$ 2.36 Billion by 2022-end
  • From 2018 to 2022, the market demand expanded at a CAGR of 6.6%
  • By Closure Type, the left atrial appendage closure segment of the market constitutes the bulk of the market with a market share of 49%
  • By End-User, the Hospitals segment dominates the market with a share of 47%
  • From 2023 to 2033, Heart Closure Devices sales are expected to flourish at a CAGR of 14.9%.
  • By 2033, the market value of Heart Closure Devices is expected to reach US$ 10.88 Billion
  • "The rise in patient pool globally, and growing awareness about heart diseases positively are the major factors driving the growth of the Heart Closure Devices Market during the forecast period," remarks an FMI analyst.

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    Competitive Landscape

    Players in the global Heart Closure Devices Market focus on expanding their global reach through various strategies, such as; partnerships, collaborations, and partnerships. The players are also making a significant investment in R&D to add innovations to their products which would help them in strengthening their position in the global market. Some of the recent developments among the key players are:

  • In July 2021, Angel Medical Systems, Inc. Announced the first commercial implantation of their flagship product, "The Guardian" device in the U.S. Region. This was the first procedure followed by their recent FDA approval.
  • In April 2021, Phoenix Cardiac Devices, Inc. Announced that they received a CE Mark for their product, BACE (Basal Annuloplasty of the Cardio externally) device. This approval helps in the commercialization of BACE in the European Union.
  • In March 2021, the U.S. FDA announced the approval of the world's first non-surgical heart valve treatment for pediatric and adult patients suffering from a native or surgically repaired right Ventricular outflow tract (RVOT). The device was specifically developed to treat patients with severe pulmonary heart regurgitation.
  • Key Companies Profiled:

  • Abbott
  • W. L. Gore & Associates, Inc.
  • Boston Scientific Corp.
  • Occlutech
  • Heartstitch
  • SMT
  • Cardia, Inc.
  • Lifetech Scientific Corp.
  • Lepu Medical Technology
  • AtriCure Inc.
  • For more Report Customization, connect with us @ https://www.Futuremarketinsights.Com/customization-available/rep-gb-15937

    Key Segments Covered in the Heart Closure Devices Industry Analysis

    Heart Closure Devices Market by Closure Type:

  • Congenital Heart Defect Closure
  • Atrial Septal Defect (ASD)
  • Patent Ductus Arteriosus (PDA)
  • Ventricular Septal Defect (VSD)
  • Patent Foramen Ovale (PFO) Closure
  • Left Atrial Appendage (LAA) Closure
  • Heart Closure Devices Market by Region:

  • North America
  • Europe
  • Asia Pacific
  • Latin America
  • Middle East & Africa (MEA)
  • About Future Market Insights (FMI)

    Future Market Insights (ESOMAR certified market research organization and a member of Greater New York Chamber of Commerce) provides in-depth insights into governing factors elevating the demand in the market. It discloses opportunities that will favor the market growth in various segments on the basis of Source, Application, Sales Channel and End Use over the next 10-years.

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    New Wrist Sensor Could Save Heart Attack Patients Critical Time In ER

    A new device designed to accurately and quickly sense whether a cardiac arrest patient also has a heart valve blockage that needs urgent treatment is now undergoing trials in Seattle.

    Cardiologists and emergency physicians at Harborview Medical Center in Seattle are testing the Tropsensor, which has been designed to detect telltale troponin levels within 3-5 minutes of being fitted on the patient's wrist.

    Troponin, a protein found in the heart muscle, appears in the bloodstream when heart damage has occurred and an artery has been blocked, signifying a heart attack. Detecting this as early as possible in patients that have arrived at the ER allowed medical staff to treat this serious condition as quickly as possible.

    Right now, triaging this condition involves an electrocardiogram (ECG), which can lack accuracy for those who have had a cardiac arrest, or a troponin blood test, which can cost an ill patient precious time waiting for pathology results.

    "Early recognition of acute coronary occlusion could allow us to rapidly restore blood flow to the heart, which improves the short- and long-term outcomes for patients who have unrecognized heart attacks," said Dr. Graham Nichol, an emergency physician at the University of Washington School of Medicine and director of Harborview's Center for Prehospital Emergency Care.

    Dr. Nichol, who is supervising the trial, added that the device could also be used on patients who present to hospital with chest pain, in order to identify any dangerous blockages.

    While cardiac arrest involves an electrical malfunction that causes the heart to stop, some patients who are resuscitated and taken to hospital have also suffered a heart attack due to a blocked artery. Identifying the blockage fast can literally mean the difference between life and death.

    The Tropsensor study will see 30 patients test the wrist device, and their outcomes will be studied over time, Dr. Nichol said, with results of the trial out next year.

    Source: University of Washington


    Measurement And Assessment Of Cardiac Function

    Cardiac Flow Velocity Measurement - Cardiac Function

    We have developed technology to allow noninvasive ultrasonic monitoring of blood flow velocity in the heart and peripheral vessels of anesthetized mice [Hartley et al, 1995; Hartley et al, 1997; Kurrelmeyer et al, 2000]. The system currently used was developed in collaboration with Indus Instruments, Houston, TX and consists of a modular Baylor ultrasonic mainframe with high-PRF 10 and 20 MHz pulsed Doppler modules, a mouse ECG amplifier with extended frequency response, a temperature monitoring and control module, a PC board with ECG electrodes and heater, several miniature pulsed Doppler probes, and an Indus Work Station for collection, storing, and analyzing ECG and Doppler signals from mice.

    The system was designed with high spatial (0.1mm) and temporal (0.1 ms) resolution for monitoring blood flow velocity in small animals with high heart rates. The Indus analyzer was developed by Dr. Hartley for mice and performs complex FFT's from the quadrature Doppler signals both in real-time for operator feedback during data acquisition and on stored signals for more detailed and higher resolution analysis. The system can measure velocities up to 5 m/s using a 10MHz probe with a 125 KHz sampling rate with temporal resolutions to 0.1 ms with full operator control of the FFT window and number of points (64-1024). The system is configured to detect the peak Doppler shift and to semi-automatically extract features such as peak and average velocities, slopes and accelerations, and areas under portions of the waveform.

    Mice are anesthetized in a chamber with isoflurane gas and maintained by delivery through a nasal cone and taped to a temperature-controlled laminated plastic board with copper electrodes placed such that the 3 bipolar limb leads allow electrocardiographic monitoring. Body fur at the left lower sternal border is clipped and the skin wetted with warm electrode gel to improve sound transmission. Cardiac Doppler signals are normally acquired by placing a 10 MHz probe over the cardiac apex below the sternum and pointing the sound beam toward the LV inflow track to record mitral velocity signals or toward the LV outflow track to record aortic velocity signals. The pulsed Doppler range gate depth is set at 4 to 7 mm to obtain optimal signals from the LV inflow and outflow tracks substernally. Repeated measures are made from each animal to allow for observation at different heart rates and to ascertain the reproducibility of the measurements. For each study, 4-6 beats are analyzed. The pulsed Doppler instrument and probes are custom made in our laboratories [Hartley et al, 1995].

    From these signals we simultaneously determine peak and mean aortic velocities and acceleration as indices of cardiac output by Doppler studies and LV systolic function, and mitral E and A velocities and their ratio E/A as indices of LV diastolic function [Taffet et al, 1996]. We found these indices to be altered in systematic ways in many of the disease models studied. For instance, in hyperthyroid mice, both systolic and diastolic indices were increased; in senescent mice, systolic indices were normal and diastolic indices were depressed. In myocardial coronary occlusions, permanently occluded mice had more depressed indices than those with reperfusion after occlusion [Michael et al, 1999].

    Peripheral Vascular Measurements – Flow Velocity and Vessel Stiffness

    Some of the mouse models we study have alterations in peripheral vascular function, arterial compliance, vascular tone, vascular impedance, and regional blood flow. In order to characterize these models we have developed several noninvasive ultrasonic methods to assess blood flow velocity in many peripheral vessels including carotid and coronary [Hartley et al, 2002; Hartley et al, 2007] and the mechanical properties of the aorta and carotid arteries. These include methods to measure pulse wave velocity as an index of vascular stiffness [Hartley et al, 1997], the direct measurement of the diameter pulsations of vessel walls [Hartley et al, 2004], and the measurement of vascular impedance spectra [Reddy et al, 2003], and the measurement of coronary blood flow velocity and coronary flow reserve [Hartley et al, 2007; Hartley et al, 2008]. We have used these methods to characterize atherosclerotic mice [Hartley et al, 2000] and the peripheral vascular adaptations to aortic banding [Li et al, 2003] and aging [Reddy et al, 2003].






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